Ten years ago I posted “The Alzheimer’s Murder Mystery,” critiquing the emphasis on anti-amyloid research and drugs. My continued curation of brain health updates came up with three articles related to and verifying that post.
My post mentioned donepezil and memantine as anti-amyloid drugs with dubious track records. Ten years later there have been more anti-amyloid drugs, with continued dubious records.
I hinted in the Murder Mystery post that other metabolic pathways should be the focus. I mentioned mitochondria and the immune system back then, which recent research validates as legitimate targets.
While a nasal spray may someday prove to be the best medical answer for dementia, I will never let go of my emphasis on lifestyle factors. An article touting combined mind-body exercise fits this bill. Though focused on people with ADHD, the pathways involved seem to me to be just as legitimate for combating cognitive decline.
I can’t help myself. I love finding out the Murder Mystery post was ten years ahead of the times. Please like and share this content. Encourage your friends to subscribe to the website as well.
